Introduction to thiamine deficiency diseases:
The other name of Vitamin B1 is thiamine and it is part of water-soluble vitamin B complex family. Only in 1890s, the Dutch medical officers Eijkman and Grins, working in Java, identified the commonalities of polyneuritis in birds and the disease beriberi in humans. On experimenting, it was found that this disease was caused due to deficiency in vitamin B1.Let us discuss more on thiamine deficiency diseases.
More facts on thiamine deficiency diseases:
The thiamine molecule similar to other B-complex vitamins is soluble in water, white crystalline solid. Thiamine is considered stable enough either in its crystallized state or in an acid solution or even when it is heated. When put in a neutral or alkaline solution thiamine displays instability, which makes it sensitive to heat, oxygen and ultraviolet light.
In infants, thiamine deficiency causes diseases like infantile beriberi thus producing edema, irritability, abdominal pain, pallor, vomiting, loss of voice and, possibly, seizures. While wet beriberi causes severe edema, which originates in the legs and goes to upper body, dry beriberi results in multiple neurologic symptoms and an emaciated appearance. Cardiomegaly, palpitations, tachycardia, dyspnea, and circulatory collapse are also rooted to thiamine deficiency. However, constipation and indigestion are common; ataxia, nystagmus, and ophthalmoplegia can also occur.
Lack of thiamine deficiency (mild in nature):
Tiredness
Irritability
Disturbance of sleep
Beriberi is a symptom for more severe thiamine deficiency;
Wernicke-Korsakoff syndrome is yet another condition caused due to severe thiamine deficiency and alcoholism
Thiamine deficiency diseases and consequences in various parts of the body:
Heart and blood vessels- Heart is enlarged, might fail to work and increases circulating blood volume.
Nervous system – This deficiency causes Polyneuritis. This affects the autonomic, sensory and motor nerves.
Eye - Thiamine deficiency may be one of the reasons for nutritional amblyopia
Gastrointestinal tract – Vitamin B1 deficiency can cause constipation with abdominal distension and colicky pains with or without anorexia, nausea, vomiting.
Conclusion for thiamine deficiency diseases:
In order to reduce cases of thiamine deficiency diseases, it is important to not only consume good wholesome foods but also take extra supplements to balance the daily intakes.
The other name of Vitamin B1 is thiamine and it is part of water-soluble vitamin B complex family. Only in 1890s, the Dutch medical officers Eijkman and Grins, working in Java, identified the commonalities of polyneuritis in birds and the disease beriberi in humans. On experimenting, it was found that this disease was caused due to deficiency in vitamin B1.Let us discuss more on thiamine deficiency diseases.
More facts on thiamine deficiency diseases:
The thiamine molecule similar to other B-complex vitamins is soluble in water, white crystalline solid. Thiamine is considered stable enough either in its crystallized state or in an acid solution or even when it is heated. When put in a neutral or alkaline solution thiamine displays instability, which makes it sensitive to heat, oxygen and ultraviolet light.
In infants, thiamine deficiency causes diseases like infantile beriberi thus producing edema, irritability, abdominal pain, pallor, vomiting, loss of voice and, possibly, seizures. While wet beriberi causes severe edema, which originates in the legs and goes to upper body, dry beriberi results in multiple neurologic symptoms and an emaciated appearance. Cardiomegaly, palpitations, tachycardia, dyspnea, and circulatory collapse are also rooted to thiamine deficiency. However, constipation and indigestion are common; ataxia, nystagmus, and ophthalmoplegia can also occur.
Lack of thiamine deficiency (mild in nature):
Tiredness
Irritability
Disturbance of sleep
Beriberi is a symptom for more severe thiamine deficiency;
Wernicke-Korsakoff syndrome is yet another condition caused due to severe thiamine deficiency and alcoholism
Thiamine deficiency diseases and consequences in various parts of the body:
Heart and blood vessels- Heart is enlarged, might fail to work and increases circulating blood volume.
Nervous system – This deficiency causes Polyneuritis. This affects the autonomic, sensory and motor nerves.
Eye - Thiamine deficiency may be one of the reasons for nutritional amblyopia
Gastrointestinal tract – Vitamin B1 deficiency can cause constipation with abdominal distension and colicky pains with or without anorexia, nausea, vomiting.
Conclusion for thiamine deficiency diseases:
In order to reduce cases of thiamine deficiency diseases, it is important to not only consume good wholesome foods but also take extra supplements to balance the daily intakes.
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